23 July 2003

Diet as Good as Levostatin in Lowering Cholesterol

Effects of a Dietary Portfolio of Cholesterol-Lowering Foods vs Lovastatin on Serum Lipids and C-Reactive Protein
David J. A. Jenkins, MD; Cyril W. C. Kendall, PhD; Augustine Marchie, BSc; Dorothea A. Faulkner, PhD; Julia M. W. Wong, RD; Russell de Souza, RD; Azadeh Emam, BSc; Tina L. Parker, RD; Edward Vidgen, BSc; Karen G. Lapsley, DSc; Elke A. Trautwein, PhD; Robert G. Josse, MB, BS; Lawrence A. Leiter, MD; Philip W. Connelly, PhD
JAMA. 2003;290:502-510.

Context: To enhance the effectiveness of diet in lowering cholesterol, recommendations of the Adult Treatment Panel III of the National Cholesterol Education Program emphasize diets low in saturated fat together with plant sterols and viscous fibers, and the American Heart Association supports the use of soy protein and nuts.

Objective: To determine whether a diet containing all of these recommended food components leads to cholesterol reduction comparable with that of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins).

Design: Randomized controlled trial conducted between October and December 2002.

Setting and Participants: Forty-six healthy, hyperlipidemic adults (25 men and 21 postmenopausal women) with a mean (SE) age of 59 (1) years and body mass index of 27.6 (0.5), recruited from a Canadian hospital-affiliated nutrition research center and the community.

Interventions: Participants were randomly assigned to undergo 1 of 3 interventions on an outpatient basis for 1 month: a diet very low in saturated fat, based on milled whole-wheat cereals and low-fat dairy foods (n = 16; control); the same diet plus lovastatin, 20 mg/d (n = 14); or a diet high in plant sterols (1.0 g/1000 kcal), soy protein (21.4 g/1000 kcal), viscous fibers (9.8 g/1000 kcal), and almonds (14 g/1000 kcal) (n = 16; dietary portfolio).

Main Outcome Measures: Lipid and C-reactive protein levels, obtained from fasting blood samples; blood pressure; and body weight; measured at weeks 0, 2, and 4 and compared among the 3 treatment groups.

Results: The control, statin, and dietary portfolio groups had mean (SE) decreases in low-density lipoprotein cholesterol of 8.0% (2.1%) (P = .002), 30.9% (3.6%) (P<.001), and 28.6% (3.2%) (P<.001), respectively. Respective reductions in C-reactive protein were 10.0% (8.6%) (P = .27), 33.3% (8.3%) (P = .002), and 28.2% (10.8%) (P = .02). The significant reductions in the statin and dietary portfolio groups were all significantly different from changes in the control group. There were no significant differences in efficacy between the statin and dietary portfolio treatments.

Conclusion: In this study, diversifying cholesterol-lowering components in the same dietary portfolio increased the effectiveness of diet as a treatment of hypercholesterolemia.

21 July 2003

United Press International Investigates: The vaccine conflict

Alternative practitioners have long argued that vaccines are a major assault on the bodies immune system and homeopaths regularly treat adults for after effects of vaccines received in childhood. The problem is exaggerated by the U.S. practice of giving multiple vaccines to infants at younger and younger ages. The Japanese take a much more careful approach to vaccination using safer vaccines administered at older ages, a practice that the U.S. would do well to follow.

Any hard look at the evidence on vaccines over the last hundred years raises many unanswered questions about effectiveness and side effects. Those of us who were "saved" from polio in the early 1960s have SV40 virus infections and some of us have cancer to go along with it. Some European countries did not implement a polio vaccination program at the time and their rates of polio dropped as fast as the U.S.. This is only one puzzling data point and their are many others.

United Press International looks at the darker side of vaccination programs. Who promotes them, and who profits from them?

UPI Investigates: The vaccine conflict
By Mark Benjamin
Investigations Editor
Published 7/20/2003 8:45 AM

WASHINGTON, July 20 (UPI) -- The screaming started four hours after 8-month-old Chaise Irons received a vaccination against rotavirus, recommended in June 1998 by the Centers for Disease Control and Prevention for every infant to prevent serious diarrhea.

Within a day he was vomiting and eliminating blood. Doctors performed emergency surgery, saving him by repairing his intestines, which were folding in on one another. A doctor later figured out the vaccine caused Chaise's problem.

In October 1999, after 15 reports of such incidents, the CDC withdrew its recommendation for the vaccination -- not because of the problem, the agency claims, but because bad publicity might give vaccines in general a bad name.

But a four-month investigation by United Press International found a pattern of serious problems linked to vaccines recommended by the CDC -- and a web of close ties between the agency and the companies that make vaccines.

20 July 2003

Hormone therapy's rise and fall

Sunday, Jul 20, 2003, front page
... Bernadine Healy, who became the first woman to lead the National Institutes of Health that year [1991], was convinced that the rush to put hormones into the hands of every woman over 50 was a reckless pursuit based on insufficient science.

"We were on a fast train to putting estrogen and progestin in every woman's drinking water," she recalled...

The stellar rise and spectacular fall of hormone replacement therapy ranks among the biggest medical mistakes in history, fueled by a combination of weak science, relentless hype, the herd mentality of doctors, and women's dawning redefinition of menopause from an inevitable "change of life" to a manageable condition.

Now, a year after the first of a series of bombshell studies demolished widely held beliefs about hormone replacement, physicians and patients alike continue to reel from the reality that the pills cause some of the very problems they aim to prevent, including heart disease and impaired mental states...

15 July 2003

Eliminating inflammation is a top priority for disease prevention

Inflammation, a normal response to infection, is a key factor in heart disease, cancer, and many other chronic diseases. It is essential that all people over 40 or anyone with a compromized immune system use the latest and most effective immune supplements. The best is Transfer Factor Plus and Dale Fawcett in Seattle at (360) 598-6585 can give you the details and lowest cost.

Any inflammation detected should be eliminated immediately by applying the right electromagnetic frequency to the organism. This will not only prevent infectious disease, it will radically reduce risk of chronic diseases.

Inflammation's infamy:
The body's first line of defense just may be the 'root of all evil'

By Karen Kreeger
The Scientist | Volume 17 | Issue 14 | 28 | Jul. 14, 2003

A finger catches the sharp edge of an envelope; a noseful of tree pollen is accidentally inhaled; the latest virus finds host after human host. In all cases the assaulted body reacts through inflammation, a well known, but not well defined process, especially its molecular cascade of events. These events are orchestrated by chemokines and the other biochemicals of innate immunity, eventually engaging downstream immune cells and antigens involved with adaptive immunity. A person is born with an innate immune system, whereas acquired immunity is developed through lifelong contact with pathogens.

Usually, inflamed tissue heals quickly, end of story. But when things go awry, the downstream immunological events, both innate and acquired, can lead to several disparate diseases. "I personally believe that chronic inflammation is the root of all evil," says Emad El-Omar, professor of gastroenterology, University of Aberdeen, UK, who works on host genetic factors associated with gastritis, a condition tied to Helicobacter pylori-related inflammation. Over the past 10 years, inflammation has been implicated as both cause and aggravating effect in a growing number of widespread, often unrelated ailments, including atherosclerosis, Alzheimer disease (AD), and some cancers.

13 July 2003

Impacts of Antibiotic-Resistant Bacteria

The impact of antibiotic resistant bacteria continues to increase. The full text of a Congressional report on this topic is available online. Antibiotics should be used for emergencies and not routine treatment. In the future, those who want to survive will use electromagnetic devices to control infection.

U.S. Congress, Office of Technology Assessment, Impacts of Antibiotic-Resistant Bacteria, OTA-H-629 (Washington, DC: U.S.
Government Printing Office, September 1995).

"Penicillin, the first antibiotic, and the more than 100 other antibiotics now available to physicians are the primary weapons in mankind's battle against bacterial diseases. They revolutionized medicine, providing cures for formerly life-threatening diseases and preventing many previously inevitable deaths from
infected wounds. They still do, but within a short time of each antibiotic's introduction into medicine, some bacteria became resistant to it, and the antibiotic lost its effectiveness against some diseases. Currently, few bacteria are resistant to all antibiotics, but many more are resistant to all but one or all but a few antibiotics, and the expectation is that resistant bacteria will continue to emerge and spread. The fear is that many bacteria will become resistant to all antibiotics, plunging humanity back into the conditions that existed in the pre-antibiotic age.

"OTA's report discusses what is known about the emergence and spread of antibiotic-resistant bacteria and describes research and development aimed at controlling those organisms. It concludes that efforts are necessary both to preserve the effectiveness of currently available antibiotics and to develop new antibiotics. It discusses issues that arise in these activities, and it presents options for taking action.

"This report was requested by the House Committee on Energy and Commerce in the 103d Congress (now the House Committee on Commerce).
The Senate Committee on Labor and Human Resources in the same Congress endorsed the request for the study."